Retinal Degeneration

Apoptotic Photoreceptor Degeneration in Experimental Retinal Detachment

Electron Microscopy / Apoptosis / Cats / Biological Sciences / DNA / Animals / Retinal detachment / Cell Death / Retinal Degeneration / Programmed cell death / Degeneration / Propidium Iodide / Nucleotides / DNA fragmentation / Animals / Retinal detachment / Cell Death / Retinal Degeneration / Programmed cell death / Degeneration / Propidium Iodide / Nucleotides / DNA fragmentation

Multiple, Parallel Cellular Suicide Mechanisms Participate In Photoreceptor Cell Death

Complement activation / Metabolism / Oxidative Stress / Autophagy / Apoptosis / Gene expression / Glucose Metabolism / Laser Capture Microdissection / Mice / Animals / Cell Death / Retinal Degeneration / Animal Model / Caspase / Optometry and Ophthalmology / Time Factors / Degeneration / Environmental Stress / Complement / Temporal Analysis / Genetic Markers / Neurosciences / Time Course / Gene Expression Regulation / Gene expression / Glucose Metabolism / Laser Capture Microdissection / Mice / Animals / Cell Death / Retinal Degeneration / Animal Model / Caspase / Optometry and Ophthalmology / Time Factors / Degeneration / Environmental Stress / Complement / Temporal Analysis / Genetic Markers / Neurosciences / Time Course / Gene Expression Regulation

Vitamins C and E reduce retinal oxidative stress and nitric oxide metabolites and prevent ultrastructural alterations in porcine hypercholesterolemia

Transmission Electron Microscopy / Oxidative Stress / Biological Sciences / Antioxidants / vitamin C / Cholesterol / Nitric oxide / Animals / Male / Retina / Hypercholesterolemia / Retinal Degeneration / Dietary Supplements / Vitamin E / Triglycerides / Lipid peroxidation / Ascorbic Acid / Swine / High Cholesterol / High Density Lipoprotein / Retinal Diseases / Superoxide Anion / Tocopherols / Total Cholesterol / Superoxides / Cholesterol / Nitric oxide / Animals / Male / Retina / Hypercholesterolemia / Retinal Degeneration / Dietary Supplements / Vitamin E / Triglycerides / Lipid peroxidation / Ascorbic Acid / Swine / High Cholesterol / High Density Lipoprotein / Retinal Diseases / Superoxide Anion / Tocopherols / Total Cholesterol / Superoxides

Multiple, Parallel Cellular Suicide Mechanisms Participate In Photoreceptor Cell Death

Complement activation / Metabolism / Oxidative Stress / Autophagy / Apoptosis / Gene expression / Glucose Metabolism / Laser Capture Microdissection / Mice / Animals / Cell Death / Retinal Degeneration / Animal Model / Caspase / Optometry and Ophthalmology / Time Factors / Degeneration / Environmental Stress / Complement / Temporal Analysis / Genetic Markers / Neurosciences / Time Course / Gene Expression Regulation / Gene expression / Glucose Metabolism / Laser Capture Microdissection / Mice / Animals / Cell Death / Retinal Degeneration / Animal Model / Caspase / Optometry and Ophthalmology / Time Factors / Degeneration / Environmental Stress / Complement / Temporal Analysis / Genetic Markers / Neurosciences / Time Course / Gene Expression Regulation

Taurine deficiency damages retinal neurones: cone photoreceptors and retinal ganglion cells

Retinal Pigment Epithelium / Gene expression / Mice / Animals / Male / Neuronal Plasticity / Retinal Degeneration / Amino Acids / Glial Fibrillary Acidic Protein / Retinal Ganglion Cells / Taurine / Guanidines / Neuronal Plasticity / Retinal Degeneration / Amino Acids / Glial Fibrillary Acidic Protein / Retinal Ganglion Cells / Taurine / Guanidines

RDH12 and RPE65, Visual Cycle Genes Causing Leber Congenital Amaurosis, Differ in Disease Expression

Psychophysics / Blindness / Membrane Proteins / Optical coherence tomography / Adolescent / Biological Sciences / Protein Structure and Function / Vision / Humans / Child / Mutation / Retina / Retinal Degeneration / Genes / Middle Aged / Adult / Human Disease / Gene Disruption / Optical Coherence Tomography (OCT) Market / Gene Transfer / Dark Adaptation / Biological Sciences / Protein Structure and Function / Vision / Humans / Child / Mutation / Retina / Retinal Degeneration / Genes / Middle Aged / Adult / Human Disease / Gene Disruption / Optical Coherence Tomography (OCT) Market / Gene Transfer / Dark Adaptation

Does hyperbaric oxygen (HBO) delivery rescue retinal photoreceptors in retinitis pigmentosa?

Treatment Outcome / Adolescent / Visual acuity / Humans / Retinitis pigmentosa / Female / Male / Retinal Degeneration / Documenta / Clinical Sciences / Middle Aged / New record / Optometry and Ophthalmology / Adult / Hyperbaric Oxygen / Hyperbaric Oxygenation / Signal to Noise Ratio / Neurosciences / Electroretinogram / Female / Male / Retinal Degeneration / Documenta / Clinical Sciences / Middle Aged / New record / Optometry and Ophthalmology / Adult / Hyperbaric Oxygen / Hyperbaric Oxygenation / Signal to Noise Ratio / Neurosciences / Electroretinogram

CD36 Deficiency Leads to Choroidal Involution via COX2 Down-Regulation in Rodents

Retinal Pigment Epithelium / Molecular Mechanics / Mice / Animals / Retinal Degeneration / Age related macular degeneration / Rats / Degeneration / Wistar Rats / Spontaneously Hypertensive Rat / Vascular Endothelial Growth Factor / Down-Regulation / Age related macular degeneration / Rats / Degeneration / Wistar Rats / Spontaneously Hypertensive Rat / Vascular Endothelial Growth Factor / Down-Regulation

A three base pair deletion encoding the amino acid (lysine-270) in the alpha-cone transducin gene

Humans / Mutation / Male / Polymerase Chain Reaction / Retinal Degeneration / Pedigree / Optometry and Ophthalmology / Genotype / Lysine / Adult / Amino Acid Sequence / Base Sequence / Transducin / Pedigree / Optometry and Ophthalmology / Genotype / Lysine / Adult / Amino Acid Sequence / Base Sequence / Transducin

Vitamins C and E Reduce Retinal Oxidative Stress and Nitric Oxide Metabolites and Prevent Ultrastructural Alterations in Porcine Hypercholesterolemia

Transmission Electron Microscopy / Oxidative Stress / Biological Sciences / Antioxidants / vitamin C / Cholesterol / Nitric oxide / Animals / Male / Retina / Hypercholesterolemia / Retinal Degeneration / Dietary Supplements / Vitamin E / Triglycerides / Lipid peroxidation / Ascorbic Acid / Swine / High Cholesterol / High Density Lipoprotein / Retinal Diseases / Superoxide Anion / Tocopherols / Total Cholesterol / Superoxides / Cholesterol / Nitric oxide / Animals / Male / Retina / Hypercholesterolemia / Retinal Degeneration / Dietary Supplements / Vitamin E / Triglycerides / Lipid peroxidation / Ascorbic Acid / Swine / High Cholesterol / High Density Lipoprotein / Retinal Diseases / Superoxide Anion / Tocopherols / Total Cholesterol / Superoxides

A model of mucopolysaccharidosis IIIB (Sanfilippo syndrome type IIIB): N-acetyl-alpha-D-glucosaminidase deficiency in Schipperke dogs

Early Childhood / Dogs / Female / Animals / Male / Retinal Degeneration / Central Nervous System / Bone marrow / Glycosaminoglycan / Clinical Sciences / Glycosaminoglycans / Heparan Sulphate / Autosomal Recessive / Clinical Signs / Purkinje cell / Retinal Degeneration / Central Nervous System / Bone marrow / Glycosaminoglycan / Clinical Sciences / Glycosaminoglycans / Heparan Sulphate / Autosomal Recessive / Clinical Signs / Purkinje cell

Taurine deficiency damages retinal neurones: cone photoreceptors and retinal ganglion cells

Retinal Pigment Epithelium / Gene expression / Mice / Animals / Male / Neuronal Plasticity / Retinal Degeneration / Amino Acids / Glial Fibrillary Acidic Protein / Retinal Ganglion Cells / Taurine / Guanidines / Neuronal Plasticity / Retinal Degeneration / Amino Acids / Glial Fibrillary Acidic Protein / Retinal Ganglion Cells / Taurine / Guanidines

Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors

Transcription Factors / Nuclear Receptor / Biological Sciences / Humans / Mice / Animals / Human Molecular Genetics / Glutathione / Retinal Degeneration / Glutathione Transferase / Orphan Nuclear Receptors / Expression analysis / DNA binding proteins / Rhodopsin / cDNA library / Transducin / Animals / Human Molecular Genetics / Glutathione / Retinal Degeneration / Glutathione Transferase / Orphan Nuclear Receptors / Expression analysis / DNA binding proteins / Rhodopsin / cDNA library / Transducin

Fibroblast growth factor receptor deficiency in dystrophic retinal pigmented epithelium

Electron Microscopy / Retinal Pigment Epithelium / Animals / Polymerase Chain Reaction / Retinal Degeneration / Cellular Physiology / Medical Physiology / Fibroblast Growth Factor / Cell nucleus / Rats / Molecular weight / Base Sequence / Cell Size / Cellular Physiology / Medical Physiology / Fibroblast Growth Factor / Cell nucleus / Rats / Molecular weight / Base Sequence / Cell Size

AIF deficiency compromises oxidative phosphorylation

Membrane Proteins / Mitochondria / Apoptosis / Biological Sciences / Phylogeny / Brain / Humans / Glucose / Mice / Animals / Retina / Retinal Degeneration / Mitochondrial Respiratory Chain / Programmed cell death / Myocardium / Oxidative phosphorylation / Yeasts / Homologous Recombination / Lactic Acid / Adenosine Triphosphate / Brain / Humans / Glucose / Mice / Animals / Retina / Retinal Degeneration / Mitochondrial Respiratory Chain / Programmed cell death / Myocardium / Oxidative phosphorylation / Yeasts / Homologous Recombination / Lactic Acid / Adenosine Triphosphate

Fibroblast growth factor receptor deficiency in dystrophic retinal pigmented epithelium

Electron Microscopy / Retinal Pigment Epithelium / Animals / Polymerase Chain Reaction / Retinal Degeneration / Cellular Physiology / Medical Physiology / Fibroblast Growth Factor / Cell nucleus / Rats / Molecular weight / Base Sequence / Cell Size / Cellular Physiology / Medical Physiology / Fibroblast Growth Factor / Cell nucleus / Rats / Molecular weight / Base Sequence / Cell Size
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